Register to attend a free NIH webinar. Attendees will learn about the research behind a proposed new automated bench-top device for labeling immunotherapy cells with 89Zr-oxine for Positron Emission Tomography (PET) tracking during treatment. The current method for labeling cells with 89Zr-oxine involves a tedious manual process requiring several rounds of centrifugation and pipetting from a highly skilled technician. However, even with a technician’s high skill level, the process suffers from low reproducibility and reliability of labeled cells.

Dr. Adler and his team are developing a device that automates the labeling process using acoustophoresis, eliminating the need for multiple manual rounds of centrifugation and pipetting, thereby substantially increasing the reproducibility and reliability of the labeled cells. This results in better treatment analysis when PET scans are used to track progress in immunotherapy or other clinical or pre-clinical applications.